Reviewed By Blake Gilliam, CRNP
Reading Time: 3 minutes
The term male menopause often confuses people because it implies a sudden hormonal shift similar to what women experience. Men do not stop producing hormones, but testosterone production declines gradually.
Table of Contents
What Is Male Menopause?
Male menopause, or andropause, describes the steady decline in testosterone levels that develops over time. Unlike female menopause, reproductive ability does not end. Instead, hormone levels fall slowly due to changes in the pituitary gland, hypothalamus, and other regulatory systems.
Most men notice changes in the late 40s to mid-50s, but some may notice changes in their 30s. Chronic illness, lifestyle factors, and underlying hormone issues can cause earlier onset.
Why Testosterone Declines Over Time
Testosterone levels naturally decline with age as the body becomes less efficient at producing and regulating hormones. This process happens gradually and varies from person to person. Certain health conditions, medications, and lifestyle factors can accelerate testosterone decline and increase the likelihood of symptoms.
Contributing factors include:
- Age-related hormone changes: Testosterone production slows over time, and free testosterone levels may decrease as binding proteins increase.
- Chronic health conditions: Obesity, diabetes, metabolic dysfunction, and cardiovascular disease are strongly associated with lower testosterone levels.
- Medications and medical treatments: Certain cancer therapies, long-term opioid use, and steroid use can suppress testosterone levels.
- Lifestyle factors: Poor sleep, chronic stress, excess alcohol use, inactivity, and weight gain can negatively affect hormone balance.
These combined factors influence how quickly testosterone levels fall.
Common Andropause Symptoms
As testosterone levels decline, many men experience a combination of physical, emotional, and cognitive changes. These changes usually develop gradually rather than appearing all at once.
Common symptoms may include but are not limited to:
- Reduced libido: Sexual interest declines and often appears as one of the earliest symptoms.
- Erectile dysfunction: Erections may weaken or become less predictable due to reduced hormone support.
- Loss of muscle mass: Strength decreases as lean tissue shifts to fat and muscle recovery slows.
- Fatigue: Energy levels drop even when sleep patterns remain stable.
- Mood changes: Irritability, low mood, or emotional swings may develop as hormone levels fall.
- Difficulty concentrating: Memory lapses and slower thinking may appear during periods of hormonal imbalance.
- Bone density loss: Decreasing testosterone weakens bone structure and raises osteoporosis risk.
Untreated low testosterone is associated with higher rates of metabolic disease, Type 2 diabetes, sleep apnea, and cardiovascular risk.
Testosterone Replacement Therapy
The most effective and evidence-based treatment for clinically low testosterone is testosterone replacement therapy. This form of hormone therapy raises hormone levels to a healthy range and reduces symptoms linked to testosterone deficiency.
At Madison Integrative Medicine, testosterone therapy commonly involves weekly or biweekly injections performed at home. This dosing schedule supports stable energy, mood, libido, and improved overall hormone balance.
What to Expect During Treatment
Testosterone replacement therapy follows a structured medical process focused on safety, accurate dosing, and ongoing monitoring.
- Diagnosis with blood tests: Blood testing confirms low testosterone levels, identifies hormone imbalances, and rules out other causes.
- Medical evaluation: At your initial consultation, we will review your medical history and assess cardiovascular risk, prostate health, and sleep apnea concerns.
- Personalized dosing: Injection doses are adjusted to maintain testosterone levels within a safe, effective range.
- Routine follow-up tests: Ongoing blood testing ensures hormone levels remain stable and treatment stays safe long term.
Testosterone replacement therapy is effective when medically supervised. A thorough medical evaluation helps determine whether treatment is appropriate for each individual.
Men’s Hormone Care in Madison, AL
If you are struggling with low energy, reduced libido, or other symptoms linked to hormonal changes, a medical evaluation can help clarify the cause. Madison Integrative Medicine offers men’s hormone care in Madison, AL focused on accurate testing and medically supervised treatment.
To schedule TRT consultation at our wellness center in Madison, AL, call (256) 325-0955 or visit us at 1230 Slaughter Rd Suite C, Madison, AL.
FAQs
What age does andropause usually begin?
Most men experience hormonal changes in their late 40s to mid-50s, though symptoms can appear earlier due to chronic illness or hormone problems.
What are the most common signs of male menopause?
Low libido, fatigue, erectile dysfunction, mood shifts, decreased muscle mass, and difficulty concentrating are the most common andropause symptoms.
Can testosterone be increased naturally?
Exercise, weight control, improved sleep, and reduced alcohol intake support hormone levels, but men with clinically low testosterone usually need testosterone replacement for meaningful improvement.
Is testosterone replacement therapy safe?
Testosterone replacement therapy is safe for men who qualify and receive ongoing monitoring. Blood tests track hormone levels, red blood cell counts, and metabolic markers. Providers assess prostate cancer risk, cardiovascular disease risk, and sleep apnea before treatment.
Does a vasectomy lower testosterone?
A vasectomy does not affect testosterone production, sexual desire, or hormone levels.
Can TRT cause hair loss?
TRT does not directly cause hair loss. Men who have genetic sensitivity to DHT (dihydrotestosterone) may notice faster progression of male pattern baldness.

